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Artocarpus lakoocha belongs to Moraceae family which also known as Ma-Haad in Thai. This plant is widely distributed in South-east Asia especially Thailand. For centuries in Thai traditional medicine, the water extract of Ma-Haad has been used for anti-helmintic.
The oxyreveratrol is a major compound found in heart wood of Ma-Haad. Oxyresveratrol exhibites potent inhibitory effect with an IC50 value of 1.2 µM on tyrosinase activity, which was is 32 times a more potent inhibition than kojic acid (IC50 40.1 µM). Oxyresveratrol has a stronger inhibition of tyrosinase on melanoma cell line than kojic acid. Oxyresveratrol offers approximately 150 times more inhibititive potency than resveratrol making the compound ideal for use as a de-pigmenting agent in the use of cosmetic skin-whitening products and medical agents for hyperpigmentation disorders, and does not exhibit any of the side-effects associated with the current market’s ‘melasma drug’ (Hydroquinone).
- Tyrosinase inhibitory activity (whitening agent)
- Potent antioxidants and free radical scavengers activity
- Potential neuroprotective effect and inhibits the apoptotic cell death
High performance liquid chromatography (HPLC) was used for control a quality of this herb extract with a quantitative and qualitative which oxyresveratrol is a marker.
- Aluminum bottle
- Plastic gallon container
Packaging can be provided in a variety of container types, depending on customs requirements.
- Dosage: 2% in cosmetic products
- Store in cool dry place, away from light, excessive heat or freezing temperatures
- Shelf life: 2 years